About UbbLE

On this website, which we named UbbLE, you can explore the findings of the scientific research* carried out by Andrea Ganna (Karolinska Institutet and Uppsala University) and Erik Ingelsson (Stanford University and Uppsala University).

This research project used data from the UK Biobank: a large-scale national health resource which aims to improve the prevention, diagnosis and treatment of many serious diseases. Between 2006 and 2010, the UK Biobank team collected a large number of measurements (variables) from over half a million UK volunteers aged 40-70. These measurements included taking blood samples, physical and biological measurements from volunteers as well as carrying out detailed questionnaires. The large-scale nature of UK Biobank makes it a unique and valuable data resource, which is available to researchers worldwide after an approved application.

We used some of this information to investigate how closely 655 variables taken from the UK Biobank participants were associated with death within five years. This association shows how accurately a variable can predict death within five years. Although this project was based on UK Biobank data, this research was carried out independently.

The two aims of UbbLE were:

  1. To investigate how well particular variables can predict death within five years. You can explore the results using the interactive Association Explorer. See the FAQs for more information.
  2. To predict the risk of dying within five years for 40-70 year old men and women living in the UK. You can get an estimate of your individual risk and calculate your ‘Ubble age’ with our Risk Calculator. See the FAQs for more information.

UbbLE has been developed as a resource for individuals, researchers, doctors and anyone working in public health and policy, and aims to improve understanding of factors that might increase or reduce life expectancy in the UK. UbbLE can be used by:

  1. Individuals to increase awareness of their health and to provide incentives for lifestyle changes.
  2. Researchers as a starting point for future research.
  3. Governmental and health organisations to inform public health advice and social policy.

For more information about this project, see our FAQs.

*Reference: Ganna A, Ingelsson E. Five-year mortality predictors: A prospective study of ~500,000 UK Biobank participants. Lancet 2015. Electronic publication ahead of print.